"****" -- Film Threat "Timely" -- Science "Compelling" -- Birth. Movies. Death.
"Not since Gattaca has a film so thoughtfully and provocatively grappled with the medical and ethical consequences of ubiquitous genomic profiling. Written and directed by the very talented Brett Bonowicz, The Perfect 46 is an engaging drama set in the plausibly near future that ought to appeal to anyone with DNA."
-- Kevin Davies, Author of "The $1,000 Genome”
"The Perfect 46 raises disturbing (and critical) questions about the seductive power of technology—and features a main character who seems not just believable, but creepily familiar. It is a classic story with a present day twist: what happens when scientific knowledge and technical know-how outrun our limited human ability to predict consequences? Striving for perfection when we have so little idea of what ”perfect” means can become the road to both societal and personal insanity."
-- KC Cole, Author of "Something Incredibly Wonderful Happens”
"It would be wrong to call The Perfect 46 a science fiction film. A decade ago that genre assignment would have been appropriate. But today, the actual science in the film has crossed over into reality, and we, as a society, will soon be grappling with the issues raised by its ultimate use in selecting healthy genes for our children. It’s not just genetic technology that is accurately portrayed but the limits imposed by randomness on all technologies. The Perfect 46 tells the very human story of both sides of the divide with lessons for all.”
-- Lee Silver, Professor of Molecular Biology, Princeton University and Co-Founder of GenePeeks Inc.
“The first film to capture the startup culture of personal genomics. Timely and provocative”
-- Misha Angrist, Author of “Here is a Human Being: At the Dawn of Personal Genomics”
"The Perfect 46 artfully depicts the very slippery slope at the intersection between genetic technology and real world eugenics. Director Brett Ryan Bonowicz provides an entertaining (and terrifying) insight into what could happen when our genomes becomes intertwined with our social network profiles."
-- Ellen Matloff, Director of Yale Cancer Genetic Counseling
"The Perfect 46 does not feel like it’s happening in some distant era. In fact, I was struck by how unfuturistic it all seemed.”
-- Susan Young, MIT Technology Review
"The Perfect 46 is science fiction that doesn’t rely on speculative science, but takes a ‘what if’ view of existing science and technology, and mixes in human drama, to tell a cautionary tale of something chillingly plausible.
-- Sci-Fi London Film Festival
“A worryingly believable cautionary tale about a geneticist who creates Perfect46.com, a matchmaking website that pairs users with their ideal genetic partner, a program that has the potential to eliminate genetic diseases and defects in future generations. Director Brett Bonowicz cuts between fake news reports and documentary interviews to create an eye-opening take on genetic ethics in the data-sharing world of social media. A thought-provoking film with an excellent lead performance from Whit Hertford — and not a single evil clone army in sight.”
-- London Evening Standard
""...a fascinating film full of challenging ideas that puts your brain to work. [Whit] Hertford delivers...a tour de force performance, creating a character that can be lauded and loathed in equal measure..."
-- Mark Bell, Film Threat
"In short: marvelous and intriguing."
-- Joanne Manaster, Scientific American